Our easy-to-use tools facilitate the protein design process#

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Our tools are standalone or can be used together at any point in your project.

PoET

Predict variant effects and create initial library designs guided by evolution.

Requires: sequence of interest

Output: library designs and predictions

Highlights

  • Introduce diversity

  • Identify mutagenesis hotspots

  • Predict variant effects

  • Rank sequence designs

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Optimization and Prediction Models (OP Models)

Design optimized variant libraries using ML models trained on your data.

Requires: data and design goals

Output: library designs and predictions

Highlights

  • Design optimized single site and combinatorial libraries

  • Create informative visuals (UMAPs, joint plots, histograms)

  • Guide design strategy based on quantitative analyses

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Structure Prediction

View and download high quality structure predictions.

Requires: sequence of interest

Output: web based visuals and .pdb files

Highlights

  • Validate designs

  • Predict multi-chain structures

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See our tools in action by visiting our Walkthroughs page